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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
RPE_HUMAN
USC-OGP 2-DE database
:
RPE_HUMAN
RPE_HUMAN
General information about the entry
View entry in simple text format
Entry name
RPE_HUMAN
Primary accession number
Q96AT9
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Ribulose-phosphate 3-epimerase; EC=5.1.3.1; AltName: Full=Ribulose-5-phosphate-3-epimerase;.
Gene name
Name=RPE
ORFNames=HUSSY-17
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1298
:
pI=5.27; Mw=23825
Cross-references
UniProtKB/Swiss-Prot
Q96AT9; RPE_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
RPE_HUMAN
Primary accession number
Q96AT9
Secondary accession number(s)
A8K4S0 B4E016 C9JPQ7 O43767 Q53TV9 Q8N215 Q96N34 Q9BSB5
Sequence was last modified on
December 1, 2001 (version 1)
Annotations were last modified on
March 15, 2017 (version 144)
Name and origin of the protein
Description
RecName: Full=Ribulose-phosphate 3-epimerase; EC=5.1.3.1; AltName: Full=Ribulose-5-phosphate-3-epimerase;
Gene name
Name=RPE
ORFNames=HUSSY-17
Encoded on
Name=RPE; ORFNames=HUSSY-17
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Carbohydrate metabolism
;
Cobalt
;
Complete proteome
;
Iron
;
Isomerase
;
Manganese
;
Metal-binding
;
Reference proteome
;
Zinc
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AK056028; BAB71076.1
; ALT_FRAME; mRNA
EMBL
AK093658; BAC04212.1
; ALT_FRAME; mRNA
EMBL
AK291035; BAF83724.1
; -; mRNA
EMBL
AK303184; BAG64278.1
; -; mRNA
EMBL
AC007038; AAX93087.1
; -; Genomic_DNA
EMBL
CH471063; EAW70473.1
; -; Genomic_DNA
EMBL
CH471063; EAW70474.1
; -; Genomic_DNA
EMBL
BC005148; AAH05148.2
; -; mRNA
EMBL
BC016764; AAH16764.1
; -; mRNA
EMBL
BC072401; AAH72401.1
; -; mRNA
EMBL
AJ224326; CAA11895.1
; -; mRNA
CCDS
CCDS2388.1; -. [Q96AT9-1]
; .
CCDS
CCDS42810.1; -. [Q96AT9-3]
; .
CCDS
CCDS63107.1; -. [Q96AT9-4]
; .
CCDS
CCDS63108.1; -. [Q96AT9-5]
; .
RefSeq
NP_001265211.1; NM_001278282.1. [Q96AT9-3]
; .
RefSeq
NP_001265212.1; NM_001278283.1. [Q96AT9-3]
; .
RefSeq
NP_001265214.1; NM_001278285.1. [Q96AT9-4]
; .
RefSeq
NP_001265215.1; NM_001278286.1. [Q96AT9-5]
; .
RefSeq
NP_001265217.1; NM_001278288.1. [Q96AT9-5]
; .
RefSeq
NP_001265218.1; NM_001278289.1
; .
RefSeq
NP_001305855.1; NM_001318926.1
; .
RefSeq
NP_001305856.1; NM_001318927.1
; .
RefSeq
NP_001305857.1; NM_001318928.1
; .
RefSeq
NP_001305858.1; NM_001318929.1
; .
RefSeq
NP_001305859.1; NM_001318930.1. [Q96AT9-5]
; .
RefSeq
NP_001305860.1; NM_001318931.1. [Q96AT9-5]
; .
RefSeq
NP_008847.1; NM_006916.2. [Q96AT9-3]
; .
RefSeq
NP_954699.1; NM_199229.2. [Q96AT9-1]
; .
RefSeq
XP_006712740.1; XM_006712677.3. [Q96AT9-5]
; .
UniGene
Hs.282260; -
; .
UniGene
Hs.591638; -
; .
UniGene
Hs.734255; -
; .
PDB
3OVP; X-ray
; 1.70 A; A/B=1-228
PDB
3OVQ; X-ray
; 2.00 A; A/B=1-228
PDB
3OVR; X-ray
; 1.95 A; A/B=1-228
PDB
3QC3; X-ray
; 2.20 A; A/B=1-224
PDBsum
3OVP; -
; .
PDBsum
3OVQ; -
; .
PDBsum
3OVR; -
; .
PDBsum
3QC3; -
; .
ProteinModelPortal
Q96AT9; -
; .
SMR
Q96AT9; -
; .
BioGrid
112040; 50
; .
IntAct
Q96AT9; 3
; .
MINT
MINT-1448309; -
; .
STRING
9606.ENSP00000352401; -
; .
iPTMnet
Q96AT9; -
; .
PhosphoSitePlus
Q96AT9; -
; .
DMDM
34924986; -
; .
EPD
Q96AT9; -
; .
MaxQB
Q96AT9; -
; .
PaxDb
Q96AT9; -
; .
PeptideAtlas
Q96AT9; -
; .
PRIDE
Q96AT9; -
; .
TopDownProteomics
Q96AT9-1; -. [Q96AT9-1]
; .
TopDownProteomics
Q96AT9-2; -. [Q96AT9-2]
; .
DNASU
6120; -
; .
Ensembl
ENST00000354506; ENSP00000346501
; ENSG00000197713. [Q96AT9-4]; .
Ensembl
ENST00000359429; ENSP00000352401
; ENSG00000197713. [Q96AT9-1]; .
Ensembl
ENST00000411934; ENSP00000389411
; ENSG00000197713. [Q96AT9-5]; .
Ensembl
ENST00000429921; ENSP00000401838
; ENSG00000197713. [Q96AT9-3]; .
Ensembl
ENST00000436630; ENSP00000403808
; ENSG00000197713. [Q96AT9-3]; .
Ensembl
ENST00000438204; ENSP00000402061
; ENSG00000197713. [Q96AT9-5]; .
Ensembl
ENST00000454822; ENSP00000394455
; ENSG00000197713. [Q96AT9-3]; .
GeneID
6120; -
; .
KEGG
hsa:6120; -
; .
UCSC
uc002vdn.5; human. [Q96AT9-1]
; .
CTD
6120; -
; .
DisGeNET
6120; -
; .
GeneCards
RPE; -
; .
H-InvDB
HIX0190555; -
; .
HGNC
HGNC:10293; RPE
; .
HPA
HPA036498; -
; .
HPA
HPA036499; -
; .
MIM
180480; gene
; .
neXtProt
NX_Q96AT9; -
; .
OpenTargets
ENSG00000197713; -
; .
PharmGKB
PA34654; -
; .
eggNOG
KOG3111; Eukaryota
; .
eggNOG
COG0036; LUCA
; .
GeneTree
ENSGT00390000001447; -
; .
HOGENOM
HOG000259349; -
; .
HOVERGEN
HBG044821; -
; .
InParanoid
Q96AT9; -
; .
KO
K01783; -
; .
OMA
KTIDVCA; -
; .
OrthoDB
EOG091G0JMQ; -
; .
PhylomeDB
Q96AT9; -
; .
TreeFam
TF300157; -
; .
BRENDA
5.1.3.1; 2681
; .
Reactome
R-HSA-71336; Pentose phosphate pathway (hexose monophosphate shunt)
; .
EvolutionaryTrace
Q96AT9; -
; .
GeneWiki
RPE_(gene); -
; .
GenomeRNAi
6120; -
; .
PRO
PR:Q96AT9; -
; .
Proteomes
UP000005640; Chromosome 2
; .
Bgee
ENSG00000197713; -
; .
CleanEx
HS_RPE; -
; .
ExpressionAtlas
Q96AT9; baseline and differential
; .
Genevisible
Q96AT9; HS
; .
GO
GO:0005829; C:cytosol
; IBA:GO_Central; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0042802; F:identical protein binding
; IPI:IntAct; .
GO
GO:0046872; F:metal ion binding
; IDA:UniProtKB; .
GO
GO:0042803; F:protein homodimerization activity
; IPI:UniProtKB; .
GO
GO:0004750; F:ribulose-phosphate 3-epimerase activity
; IDA:UniProtKB; .
GO
GO:0005975; P:carbohydrate metabolic process
; IDA:UniProtKB; .
GO
GO:0044262; P:cellular carbohydrate metabolic process
; IBA:GO_Central; .
GO
GO:0019323; P:pentose catabolic process
; IBA:GO_Central; .
GO
GO:0006098; P:pentose-phosphate shunt
; IDA:UniProtKB; .
GO
GO:0009052; P:pentose-phosphate shunt
; non-oxidative branch; IBA:GO_Central
CDD
cd00429; RPE
; 1; .
Gene3D
3.20.20.70; -
; 1; .
InterPro
IPR013785; Aldolase_TIM
; .
InterPro
IPR026019; Ribul_P_3_epim
; .
InterPro
IPR000056; Ribul_P_3_epim-like
; .
InterPro
IPR011060; RibuloseP-bd_barrel
; .
PANTHER
PTHR11749; PTHR11749
; 1; .
Pfam
PF00834; Ribul_P_3_epim
; 1; .
PIRSF
PIRSF001461; RPE
; 1; .
SUPFAM
SSF51366; SSF51366
; 1; .
TIGRFAMs
TIGR01163; rpe
; 1; .
PROSITE
PS01085; RIBUL_P_3_EPIMER_1
; 1; .
PROSITE
PS01086; RIBUL_P_3_EPIMER_2
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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